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Tag: Flow Cast

Clinical Applications of the Basophil Activation Test in Food Allergy

Download eBOOK Webinar Recording Webinar Overview Abstract The basophil activation test has emerged as a novel diagnostic test for food allergy. Being a functional test, it has the potential to closely resemble the clinical phenotype of patients following allergen exposure. The basophil activation test can be seen as an in vitro challenge, where instead of
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Webinar: The Application of Data-Driven Approaches to Flow Cytometric Analysis of Basophil Activation Testing

Using Flow CAST® for the Development of a High Throughput, Objective Approach to Basophil Activation Image credit: Sarita U. Patil et al. (full citation below) DOWNLOAD eBOOK Webinar Recording Abstract We have developed and implemented a new data-driven, programmatic approach to the analysis of flow cytometry data from basophil activation testing. While conventional data analysis of flow
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Flow CAST® eBook- Kinase Inhibition Assay for BTK, SYK, and PI3K Activity

Flow CAST® eBook Testing Potency and Efficacy of Inhibitors of PI3K, PI3K, BTK and SYK Activity Biomarker assays are developed specifically for pharmacokinetic and pharmacodyamic (PK/PD) models during drug discovery and are often used to test efficacy and toxicity. Inhibitors of PI3K, SYK and BTK pathways are a large focus for pharmaceutical companies with several
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Testing Potency and Efficacy of Inhibitors of P13K, SYK, BTK Activity

The Flow CAST® is intended for the determination of basophil activation in whole blood samples by flow cytometry. Our unique marker combination – CCR3 and CD63 – combines the simple gating properties for basophil detection by CCR3 with the solid application of the proven activation marker CD63 in one. Thanks to its easy protocol and smart
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