Flow Cast Archives - Buhlmann Diagnostics Corp

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Flow CAST- Assay Overview Video

Flow CAST®: Research Use Only in the US. Not for diagnostic procedures. Health Canada License:101781 BÜHLMANN Flow CAST® and Basophil Activation (BAT): Basophil Activation Tests (BAT) have been extensively studied as in vitro functional assays and have demonstrated superior accuracy as compared to other blood tests for various allergies (1).  BÜHLMANN  provides a broad range of
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Basophils Are Still Alive

Quality Assay & Sample Stability for Viable Basophils Basophil Activation Testing (often referred to as BAT) is a flow-cytometry-based functional assay that assesses the degree of cell activation after exposure to stimuli.3 Q: Do you know which BAT application makes sense for your lab? Are you thinking about implementing an allergy BAT?  Or are you
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Functional and Phenotypic Analysis of Basophils Allows Determining Distinct Subtypes in Patients with Chronic urticaria

Flow CAST® Assay: Rauber MM, Pickert J, Holiangu L, Möbs C, Pfützner W. Functional and phenotypic analysis of basophils allows determining distinct subtypes in patients with chronic urticaria. Allergy. 2017 Dec;72(12):1904-1911. . Epub 2017 Jul 12. PubMed PMID: 28585360; doi:10.1111/all.13215 Highlights from this Publication “CU can be categorized into three immunologic subgroups based on their basophil
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Positive CD63 Basophil Activation Tests Are Common in Children with Chronic Spontaneous Urticaria and Linked to High Disease Activity

Flow CAST® Assay:   Netchiporouk E, Moreau L, Rahme E, Maurer M, Lejtenyi D, Ben-Shoshan M. Positive CD63 Basophil Activation Tests Are Common in Children with Chronic Spontaneous Urticaria and Linked to High Disease Activity. Int Arch Allergy Immunol. 2016;171(2):81-88. Epub 2016 Nov 16. PubMed PMID:27846634; doi:  10.1159/000451084. Highlights from this Publication “Our study provides, for the
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Basophil Activation Test Identifies the Patients with Chronic Spontaneous Urticaria Suffering the Most Active Disease

Flow CAST® Assay: Curto-Barredo L, Yelamos et al. Basophil Activation Test identifies the patients with Chronic Spontaneous Urticaria suffering the most active disease. Immun Inflamm Dis. 2016 Oct 4;4(4):441-445. eCollection 2016 Dec. PubMed PMID: 27980778; doi:  10.1002/iid3.125. Highlights from this Publication “BAT was performed, measuring expression of the CD63 surface marker on basophils from whole blood by
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Assessment of Sensitization to Grape and Wine Allergens as Possible Causes of Adverse Reactions to Wine: A Pilot Study

Flow CAST® Assay: Jaeckels N, Bellinghausen I, Fronk P, Heydenreich B, Saloga J, Decker H. Assessment of sensitization to grape and wine allergens as possible causes of adverse reactions to wine: a pilot study. Clin Transl Allergy. 2015 Jun 22;5:21.PMID: 26101585  DOI: 10.1186/s13601-015-0065-8 Highlights from this Publication This article show the unique potential of BAT testing for studying specific allergies when
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Correlations Between Basophil Activation, Allergen-Specific IgE with Outcome and Severity of Oral Food Challenges

Flow CAST® Assay: Song Y, Wang J, Leung N, Wang LX, Lisann L, Sicherer SH, Scurlock AM, Pesek R, Perry TT, Jones SM, Li XM. Correlations between basophil activation, allergen-specific IgE with outcome and severity of oral food challenges. Ann Allergy Asthma Immunol. 2015 Apr;114(4):319-26. PubMed PMID: 25841330.  doi: 10.1016/j.anai.2015.01.006 Highlights from this Publication “..These results indicate
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Markers of Tolerance Development to Food Allergens

BAT Relevant Literature: Ponce M, Diesner SC, Szépfalusi Z, Eiwegger T. Markers of tolerance development to food allergens. Allergy. 2016 Oct;71(10):1393-404. Epub 2016 Jul 11. Review.  PMID: 27286276 DOI: 10.1111/all.12953 Highlights from this Publication “Biomarkers that predict tolerance development as compared to desensitization are needed. This is decisive to consult patients on treatment duration and risk behavior if OIT
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Making the Most of In Vitro Tests to Diagnose Food Allergy

BAT Relevant Literature: Santos AF, Brough HA. Making the Most of In Vitro Tests to Diagnose Food Allergy. J Allergy Clin Immunol Pract. 2017 Mar - Apr;5(2):237-248. PMID: 28283150  DOI: 10.1016/j.jaip.2016.12.003. Highlights from this Publication “Various in vitro tests assess different aspects of the underlying immune mechanism of IgE-mediated food allergy. Some can be used for diagnostic
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Road Map for the Clinical Application of the Basophil Activation Test in Food Allergy

BAT Relevant Literature: Santos AF, Shreffler WG. Road map for the clinical application of the basophil activation test in food allergy. Clin Exp Allergy. 2017 Sep;47(9):1115-1124. doi: 10.1111/cea.12964. Epub 2017 Aug 1. Review. PubMed PMID: 28618090 DOI: 10.1111/cea.12964 . Highlights from this Publication “..BAT is sensitive and more specific than standard testing and has the potential to reduce
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