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PI3K-δ and PI3K-γ Inhibition by IPI-145 Abrogates Immune Responses and Suppresses Activity in Autoimmune and Inflammatory Disease Models

Flow CAST® – Kinase Inhibtion Assay Citation: Winkler, DG et al. PI3K-δ and PI3K-γ inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models. Chem Biol. 2013 Nov 21;20(11):1364-74. doi: 10.1016/j.chembiol.2013.09.017. Epub 2013 Nov 7. PMID: 24211136. "These studies demonstrate that IPI-145 exerts profound effects on adaptive and innate immunity by inhibiting
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FOCUS: Future of Fecal Calprotectin Utility Study in Inflammatory Bowel Disease

BÜHLMANN Quantum Blue® fCAL Citation: Rosenfeld G, Greenup A-J, Round A, et al. FOCUS: Future of fecal calprotectin utility study in inflammatory bowel disease. World Journal of Gastroenterology. 2016;22(36):8211-8218. doi:10.3748/wjg.v22.i36.8211. PMID:27688663. Highlight from this Publication "The FC test effected a change in management 51.3% of the time and receipt of the result was associated with a reduction
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BUHLMANN Highlights: Neuroimmune Biomarkers, Esoteric Testing, and Utilization in Research

BÜHLMANN Neuroimmunology Assays Simple, Esoteric Testing for Important Neuroimmune Biomarkers The BÜHLMANN Neuroimmunology product line is a list of robust assays for simple, esoteric testing for important neuroimmune biomarkers and it is supported by numerous clinical publications.  Learn More About: Benefits, Features and Highlights of BÜHLMANN Neuroimmunology Assays BÜHLMANN Assay Kit Citations- See how these assays were used
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CAL-101, A p110delta Selective Phosphatidylinositol-3-Kinase Inhibitor for the Treatment of B-cell Malignancies, Inhibits PI3K Signaling and Cellular Viability

Flow CAST® - Kinase Inhibition Assay Citation: Lannutti, B.J. et al. CAL-101, a p110δ selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability. Blood. 2011 Jan 13; 117(2): 591-594. PMID: 20959606. "We have thus described the biochemical and cellular activity of CAL-101, a selective and potent inhibitor of p110δ; such targeted
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A Novel Turbidimetric Immunoassay for Fecal Calprotectin Optimized for Routine Chemistry Analyzers

BÜHLMANN fCAL® turbo Citation: Nilsen, T. et. al.  A novel turbidimetric immunoassay for fecal calprotectin optimized for routine chemistry analyzers. J Clin Lab Anal. 2016 Sep 15. PMID:27629827 The publication describes the technical performance of the turbidimetric assay on the cobas c501 and the Mindray BS-380. Highlight from this Publication Short assay time of 10 min with
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Review BUHLMANN Products- Get $20 Amazon Gift Card

Are you using BÜHLMANN products and want to leave a comment on Biocompare? BÜHLMANN offers a wide variety of products including ELISA kits, RIA  kits, lateral flow assays, flow cytometry assays and turbidimetric assays. If you have used any of the assays in our product portfolio please share your experience with researchers around the world and you
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BUHLMANN announces new Microsite for Kinase Inhibition Assay

BÜHLMANN’s Kinase Inhibition Assay Testing Potency and Efficacy of Inhibitors of PI3K δ, PI3K γ, BTK and SYK Activity Biomarker assays are developed specifically for pharmacokinetic and pharmacodyamic (PK/PD) models during drug discovery and are often used to test efficacy and toxicity. Inhibitors of PI3K, BTK and SYK pathways are a large focus for pharmaceutical
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High-Dose Rituximab and Anti-MAG-Associated Polyneuropathy

Anti-MAG Autoantibodies ELISA Citation: Renaud S et al.; High-dose rituximab and anti-MAG-associated polyneuropathy. Neurology. 2006 Mar 14; 66(5):742-4. PMID:16534115 Read Citation Anti-MAG Autoantibodies ELISA is for Research Use Only.  Not for use in diagnostic procedures in the US. Health Canada License: 89118
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Anti-Myelin-Associated Glycoprotein Neuropathy

Anti-MAG Autoantibodies ELISA Citation: Steck AJ et al.; Anti-myelin-associated glycoprotein neuropathy; Curr Opin Neurol. 2006 Oct; 19(5): 458-63. Review. PMID:16969155 Read Citation Anti-MAG Autoantibodies ELISA  is for Research Use Only.  Not for use in diagnostic procedures in the US. Health Canada License: 89118
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Further Comparisons of Assays for Detecting MAG IgM Autoantibodies

Anti-MAG Autoantibodies ELISA Citation: Jaskowski TD et al.; Further comparisons of assays for detecting MAG IgM autoantibodies; J Neuroimmunol. 2007 Jul; 187(1-2): 175-8. PMID:17537521 Highlight from this Publication “EIA detected low titers of MAG IgM antibodies in suspected [subject] sera (negative by other methods) that were also SGPG IgM-positive.” Read Citation Anti-MAG Autoantibodies ELISA  is for Research Use
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