BUHLMANN News

Fecal Calprotectin is Equally Sensitive in Crohn’s Disease Affecting the Small Bowel and Colon

BÜHLMANN fCAL® ELISA Citation: Jensen, M.D.,  Kjeldsen J, Nathan T. Fecal calprotectin is equally sensitive in Crohn’s disease affecting the small bowel and colon. Scand J Gastroenterol. 2011 Jun;46(6):694-700. doi: 10.3109/00365521.2011.560680. “The first study to show that fecal calprotectin is equally sensitive in colonic and small bowel CD.” Read More
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Comparison of Two Immunoassays for Measurement of Faecal Calprotectin in Detection of Inflammatory Bowel Disease: (Pre)-analytical and Diagnostic Performance Characteristics

Quantum Blue®  fCAL Citation Oyaert, M, Trouvé C, Baert F, De Smet D, Langlois M, Vanpoucke H.  Comparison of two immunoassays for measurement of faecal calprotectin in detection of inflammatory bowel disease: (pre)-analytical and diagnostic performance characteristics. Clin Chem Lab Med. 2014 Mar;52(3):391-7. doi: 10.1515/cclm-2013-0699. “The Thermo Fisher device is not reliable for extraction of faecal calprotectin.”
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Comparative Study of the Quantum Blue Rapid Test and an Established ELISA Method

Quantum Blue®  fCAL Citation Coorevits, L, Baert F , Vanpoucke H.  Faecal calprotectin: comparative study of the Quantum Blue rapid test and an established ELISA method, Clinical chemistry and laboratory medicine: CCLM / FESCC. . 2013 Apr; 51(4):825-31. DOI:10.1515/cclm-2012-0386. “…we may conclude that the POCT can serve as reliable alternative to the time consuming ELISA…” Read More
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A New Rapid Test for Fecal Calprotectin Predicts Endoscopic Remission and Postoperative Recurrence in Crohn’s Disease.

Quantum Blue®  fCAL Citation Lobatón, T, , López-García A, Rodríguez-Moranta F, Ruiz A, Rodríguez L, Guardiola J. A new rapid test for fecal calprotectin predicts endoscopic remission and postoperative recurrence in Crohn's disease. Journal of Crohn's & colitis. J Crohns Colitis. 2013 Dec; 7(12):e641-51. doi: 10.1016/j.crohns.2013.05.005. “FC determined by rapid quantitative test predicts “endoscopic remission” and
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Validation of a Point-of-Care Desk Top Device to Quantitate Fecal Calprotectin and Distinguish Inflammatory Bowel Disease from Irritable Bowel Syndrome

Quantum Blue®  fCAL Citation Sydora, M. J., Sydora BC, Fedorak RN, 2012, Validation of a point-of-care desk top device to quantitate fecal calprotectin and distinguish inflammatory bowel disease from irritable bowel syndrome, J Crohns Colitis. 2012 Mar;6(2):207-14. doi: 10.1016/j.crohns.2011.08.008. “Quantum Blue Reader® calprotectin levels were available within 30 min and correlated well with results derived
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Value Fecal Calprotectin in the Evaluation of Patients with Abdominal Discomfort: An Observational Study

BÜHLMANN fCAL® ELISA Citation Manz, M,  Burri E, Rothen C, Tchanguizi N, Niederberger C, Rossi L, Beglinger C, Lehmann FS. Value of fecal calprotectin in the evaluation of patients with abdominal discomfort: an observational study. BMC Gastroenterol. 2012 Jan 10;12:5. doi: 10.1186/1471-230X-12-5. “All together, those results support the concept that fecal calprotectin is a useful marker in
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Monoclonal antibody testing for fecal calprotectin is superior to Polyclonal Testing of Fecal Calprotectin and Lactoferrin to Identify Organic Intestinal Disease in Patients with Adominal Discomfort

BÜHLMANN fCAL® ELISA Citation Burri E, Manz M., Rothen C, Rossi L,Beglinger C, Lehmann S. Monoclonal antibody testing for fecal calprotectin is superior to polyclonal testing of fecal calprotectin and lactoferrin to identify organic intestinal disease in patients with abdominal discomfort. Clinica Chimica Acta. 2013 Feb; 416: 41-47.  doi: 10.1016/j.cca.2012.11.008 “…we demonstrated, that the diagnostic accuracy of monoclonal
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Comparison of Six Different Calprotectin Assays for the Assessment of Inflammatory Bowel Disease

Quantum Blue® fCAL Citation Labaere, D, Smismans A, Olmen A, Christiaens P, D’Haens G, Moons V, Cuyle P, Frans J, and Bossuyt P. Comparison of six different calprotectin assays for the assessment of inflammatory bowel disease, United European Gastroenterology J. 2014 Feb; 2(1): 30–37.  doi:  10.1177/2050640613518201 "The EliA [Phadia] cut off for diagnosis was optimal at a level of 15 mg/g. This is as low as
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Fecal Calprotectin: Towards a Standardized Use for Inflammatory Bowel Disease Management in Routine Practice

Value of Fecal Calprotectin in the Diagnosis of IBD: Edouard, Louis. Fecal calprotectin: towards a standardized use for inflammatory bowel disease management in routine practice. Journal of Crohn's and Colitis, 2015, 1–3 doi:10.1093/ecco-jcc/jju012. “…fecal calprotectin as a unique first line test would be sufficient to decide in which patient to perform further endoscopic or medical imaging
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Flow CAST® eBook- Kinase Inhibition Assay for BTK, SYK, and PI3K Activity

Flow CAST® eBook Testing Potency and Efficacy of Inhibitors of PI3K, PI3K, BTK and SYK Activity Biomarker assays are developed specifically for pharmacokinetic and pharmacodyamic (PK/PD) models during drug discovery and are often used to test efficacy and toxicity. Inhibitors of PI3K, SYK and BTK pathways are a large focus for pharmaceutical companies with several
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