BÜHLMANN fCAL® turbo Calprotectin Assay Highlights

BÜHLMANN fCAL® turbo is for Research Use Only. Not to be used in diagnostic procedures.
Health Canada License: 96808

Unique in Speed, Quality, Flexibility

BÜHLMANN fCAL® turbo the turbidimetric immunoassay, is a flexible solution to be applied on most clinical chemistry analyzers. The technology implements a further milestone in fecal calprotectin quantification. It offers significant advantages over other competing methods in the market and is supported by publications in the field.


  • Speed: results within 10 minutes
  • Quality: This assay is standardized against the well established BÜHLMANN fCAL® ELISA and the PETIA methodolgy enhances precision and reproducibility.
  • Flexibility: Immunoturbiometric assays can be applied to most clinical chemistry platforms, allows random access workflow which can be directly integrated into the existing laboratory infrastructure.

Combined with the  CALEX®CAP extraction device, the fecal calprotectin workflow is further simplified thus reducing hands on time dramatically.

Advantages: BÜHLMANN fCAL® turbo

Proven Standardization

  • Based on partially purified human protein
  • More than 55 peer reviewed publications, use of grey zone proven in publications
  • Commutable results: fCAL® turbo to fCAL® ELISA (see data below)

Simplest Extraction Method in the Market

  • Pre-filled tubes: BÜHLMANN’s CALEX Cap® contains 5ml of stool extraction buffer in hygienic, closed system
  • Efficient Extraction: convenient, reliable sampling of stool using 1:500 dilution
  • Extract Stability:  3 days at RT, 18 months at -20°C

Speed: Short Analysis Time 

  • Analysis time of 10 minutes and TAT including extraction procedure is 30 minutes
  • Large Measuring Range: 20-8000 μg/g

Flexible and Individual Solutions

  • Applicable on most clinical chemistry analyzers
  • Large and growing list of validated protocols (see list below)
  • Safe Stool Extracts: Stool extracts can applied without any concern of system contamination (see data below)

Disadvantages: Competitor A’s Assay 

Poor Standardization

  • Based on recombinant protein
  • Only one study published, no grey zone proposed, high calprotectin levels tend to be underestimated.
  • Results lower than Competitor A’s ELISA and Unstable calibrator (6 hours at room temp)

Laborious extraction procedure

  • No pre-filled extraction devices
  • Extraction method (~45 minutes) requires multiple pipeting and other vortexing steps
  • Large differences in results between manual extraction and device extraction

Prolonged Time to First Result 

  • 3.5 times longer (system occupation): Time to first result is ~75 min (incl. extraction)
  • Limited measuring range: 5-800 µg/g

Limited Individual Solutions

  • Only applicable on DiaSorin LIAISON and LIAISON XL

canada Learn more about measuring range, CALEX®  Cap extraction device, and assay standardization for use in Canada.

Learn about safe stool extract application on clinical chemistry platforms with BÜHLMANN fCAL® turbo and CALEX® Cap .

united-states-of-america Learn more about measuring range, CALEX®  Cap extraction device, and assay standardization for use in the US.

Learn more about BÜHLMANN fCAL® turbo commutability to the BÜHLMANN fCAL® ELISA




View Analyzer List

Check out our full list of clinical chemistry analyzers that have been validated for use with the BÜHLMANN fCAL® turbo Assay.

Contact Collin or Jennifer today  (Click on their email below) for more details on the BÜHLMANN fCAL® turbo automated calprotectin assay.

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