Tag: Flow Cast

Webinar: The Application of Data-Driven Approaches to Flow Cytometric Analysis of Basophil Activation Testing

Using Flow CAST® for the Development of a High Throughput, Objective Approach to Basophil Activation Image credit: Sarita U. Patil et al. (full citation below) Webinar Recording Abstract We have developed and implemented a new data-driven, programmatic approach to the analysis of flow cytometry data from basophil activation testing. While conventional data analysis of flow cytometric data
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Flow CAST® eBook- Kinase Inhibition Assay for BTK, SYK, and PI3K Activity

Flow CAST® eBook Testing Potency and Efficacy of Inhibitors of PI3K, PI3K, BTK and SYK Activity Biomarker assays are developed specifically for pharmacokinetic and pharmacodyamic (PK/PD) models during drug discovery and are often used to test efficacy and toxicity. Inhibitors of PI3K, SYK and BTK pathways are a large focus for pharmaceutical companies with several
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Testing Potency and Efficacy of Inhibitors of P13K, SYK, BTK Activity

Inhibitors of PI3K, SYK and BTK pathways are a large focus for pharmaceutical companies with several small molecule inhibitors currently at different stages of development. Enzymatic assays measuring the direct activity of compounds are limited because they do not provide information about the entire pathway controlled by these kinases. If you are interested in learning
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